New details from the No Rest for the Wicked showcase:

• World is handcrafted, not procedurally generated.
• Randomized loot.
• WASD / Analog Stick movement, not point and click.
• Day and night cycle.
• Dynamic weather.
• Animation driven combat, inspired by ARPGs, action games, and fighting games.
• Gear has 4 different rarities from highly customizable white items to unique gold items.
• Weapons can drop with a specific rune, which can then be extracted.
• Each weapon type has a different moveset.
• Sacrament is the capital city.
• You can buy houses and properties in Sacrament.
• Collect and harvest resources, which can be used to craft gear or items for your home.
• Regions you've visited before can have drastically different enemies.
• Endgame crucibles will be in the game at launch.
• Combat is similar to Dark Souls. Armor weight affects movement.
• Enemies don't respawn when you die, injured enemies will stay injured after you respawn.
• Coming to Steam Early Access on April 18th (console versions will launch with version 1.0).